Searchable abstracts of presentations at key conferences in endocrinology

ea0099ep890 | Pituitary and Neuroendocrinology | ECE2024

Temozolomide therapy in an aggressive ACTH-producing pituitary tumour

Redondo de Carvalho Ines , Fernandes Goncalo , Sobral do Rosario Francisco

Introduction: Aggressive pituitary tumours are rare (<2% of pituitary macroadenomas) and are characterized by local invasiveness, progressive growth, and multiple recurrences despite conventional treatments. Approximately 30-40% of these tumours are functioning corticotroph adenomas. Diagnosis relies on clinical, imaging evaluation with magnetic resonance imaging (MRI), hormonal, and pathological assessments. Its therapeutic approach is challenging.C...

ea0099ep891 | Pituitary and Neuroendocrinology | ECE2024

Mucocutaneous diathesis in severe cushing disease

Redondo de Carvalho Ines , Carda Jose , Tavares Bello Carlos , Esperanca Isabel , Sobral do Rosario Francisco

Introduction: Cushing syndrome is a complex disease with multisystemic manifestations. It includes skin and connective tissue abnormalities, in which glucocorticoids reduce the synthesis and production of collagen, resulting in skin thinning, subcutaneous vascular tissue frailty and mucocutaneous bleeding. Case report: A 59-year-old woman with history of hypertension, type 2 diabetes, hypercholesterolemia, and chronic kidney disease, was admitted to the ...